Cargando…
Biochemical Features of a Catalytic Antibody Light Chain, 22F6, Prepared from Human Lymphocytes
Human antibody light chains belonging to subgroup II of germ line genes were amplified by a seminested PCR technique using B-lymphocytes taken from a human adult infected with influenza virus. Each gene of the human light chains was transferred into the Escherichia coli system. The recovered light c...
Autores principales: | Hifumi, Emi, Fujimoto, Naoko, Arakawa, Mitsue, Saito, Eri, Matsumoto, Shingo, Kobayashi, Nobuyuki, Uda, Taizo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707657/ https://www.ncbi.nlm.nih.gov/pubmed/23677996 http://dx.doi.org/10.1074/jbc.M113.454579 |
Ejemplares similares
-
A new catalytic site functioning in antigen cleavage by H34 catalytic antibody light chain
por: Hifumi, Emi, et al.
Publicado: (2022) -
New technologies to introduce a catalytic function into antibodies: A unique human catalytic antibody light chain showing degradation of β‐amyloid molecule along with the peptidase activity
por: Hifumi, Emi, et al.
Publicado: (2019) -
Finding and characterizing a catalytic antibody light chain, H34, capable of degrading the PD-1 molecule
por: Hifumi, Emi, et al.
Publicado: (2020) -
Obtaining Highly Active Catalytic Antibodies Capable of Enzymatically Cleaving Antigens
por: Nonaka, Tamami, et al.
Publicado: (2022) -
Direct conversion of a general antibody to its catalytic antibody and corresponding applications —Importance and role of Pro95 in CDR-3—
por: HIFUMI, Emi, et al.
Publicado: (2023)