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Insulin receptor membrane retention by a traceable chimeric mutant
BACKGROUND: The insulin receptor (IR) regulates glucose homeostasis, cell growth and differentiation. It has been hypothesized that the specific signaling characteristics of IR are in part determined by ligand-receptor complexes localization. Downstream signaling could be triggered from the plasma m...
Autores principales: | Giudice, Jimena, Jares-Erijman, Elizabeth A, Leskow, Federico Coluccio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707766/ https://www.ncbi.nlm.nih.gov/pubmed/23805988 http://dx.doi.org/10.1186/1478-811X-11-45 |
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