Cargando…

Non-synonymous single-nucleotide variations of the human oxytocin receptor gene and autism spectrum disorders: a case–control study in a Japanese population and functional analysis

BACKGROUND: The human oxytocin receptor (hOXTR) is implicated in the etiology of autism spectrum disorders (ASDs) and is a potential target for therapeutic intervention. Several studies have reported single-nucleotide polymorphisms (SNPs) of the OXTR gene associated with ASDs. These SNPs, however, r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Wen-Jie, Hashii, Minako, Munesue, Toshio, Hayashi, Kenshi, Yagi, Kunimasa, Yamagishi, Masakazu, Higashida, Haruhiro, Yokoyama, Shigeru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707786/ https://www.ncbi.nlm.nih.gov/pubmed/23815867 http://dx.doi.org/10.1186/2040-2392-4-22

Ejemplares similares

Association Study between the CD157/BST1 Gene and Autism Spectrum Disorders in a Japanese Population
por: Yokoyama, Shigeru, et al.
Publicado: (2015)

One Single Nucleotide Polymorphism of the TRPM2 Channel Gene Identified as a Risk Factor in Bipolar Disorder Associates With Autism Spectrum Disorder in a Japanese Population
por: Mahmuda, Naila Al, et al.
Publicado: (2020)

A Study of Single Nucleotide Polymorphisms of the SLC19A1/RFC1 Gene in Subjects with Autism Spectrum Disorder
por: Mahmuda, Naila Al, et al.
Publicado: (2016)

Social Interaction Improved by Oxytocin in the Subclass of Autism with Comorbid Intellectual Disabilities
por: Higashida, Haruhiro, et al.
Publicado: (2019)

Oxytocin for Male Subjects with Autism Spectrum Disorder and Comorbid Intellectual Disabilities: A Randomized Pilot Study
por: Munesue, Toshio, et al.
Publicado: (2016)

Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism
por: Cherepanov, Stanislav M., et al.
Publicado: (2021)

Enhanced brain signal variability in children with autism spectrum disorder during early childhood
por: Takahashi, Tetsuya, et al.
Publicado: (2015)

Infant Stimulation Induced a Rapid Increase in Maternal Salivary Oxytocin
por: Minami, Kana, et al.
Publicado: (2022)

Synchrony of auditory brain responses predicts behavioral ability to keep still in children with autism spectrum disorder: Auditory-evoked response in children with autism spectrum disorder
por: Yoshimura, Yuko, et al.
Publicado: (2016)

Attentional Control and Interpretation of Facial Expression after Oxytocin Administration to Typically Developed Male Adults
por: Hirosawa, Tetsu, et al.
Publicado: (2015)

Nicotinamide riboside supplementation corrects deficits in oxytocin, sociability and anxiety of CD157 mutants in a mouse model of autism spectrum disorder
por: Gerasimenko, Maria, et al.
Publicado: (2020)

RAGE regulates oxytocin transport into the brain
por: Yamamoto, Yasuhiko, et al.
Publicado: (2020)

Oxytocin attenuates feelings of hostility depending on emotional context and individuals' characteristics
por: Hirosawa, Tetsu, et al.
Publicado: (2012)

Salivary Oxytocin Concentrations in Seven Boys with Autism Spectrum Disorder Received Massage from Their Mothers: A Pilot Study
por: Tsuji, Shuji, et al.
Publicado: (2015)

Two oxytocin analogs, N-(p-fluorobenzyl) glycine and N-(3-hydroxypropyl) glycine, induce uterine contractions ex vivo in ways that differ from that of oxytocin
por: Cherepanov, Stanislav M., et al.
Publicado: (2023)

Somato-axodendritic release of oxytocin into the brain due to calcium amplification is essential for social memory
por: Higashida, Haruhiro
Publicado: (2015)

Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus during Social or Psychological Stress in Mice
por: Zhong, Jing, et al.
Publicado: (2016)

Structure‐specific effects of lipidated oxytocin analogs on intracellular calcium levels, parental behavior, and oxytocin concentrations in the plasma and cerebrospinal fluid in mice
por: Cherepanov, Stanislav M., et al.
Publicado: (2017)

The Roles of Oxytocin and CD38 in Social or Parental Behaviors
por: Lopatina, Olga, et al.
Publicado: (2013)

Effects of Three Lipidated Oxytocin Analogs on Behavioral Deficits in CD38 Knockout Mice
por: Cherepanov, Stanislav M., et al.
Publicado: (2017)

Oxytocin-Trust Link in Oxytocin-Sensitive Participants and Those Without Autistic Traits
por: Kurokawa, Hirofumi, et al.
Publicado: (2021)

Oral Supplementation with Maca Improves Social Recognition Deficits in the Valproic Acid Animal Model of Autism Spectrum Disorder
por: Fu, Pinyue, et al.
Publicado: (2023)

Oxytocin-induced increase in N,N-dimethylglycine and time course of changes in oxytocin efficacy for autism social core symptoms
por: Kato, Yasuhiko, et al.
Publicado: (2021)

Oxytocin efficacy is modulated by dosage and oxytocin receptor genotype in young adults with high-functioning autism: a 24-week randomized clinical trial
por: Kosaka, H, et al.
Publicado: (2016)

Neurobiological Aspects of Face Recognition: The Role of Oxytocin
por: Lopatina, Olga L., et al.
Publicado: (2018)

Altered brain connectivity in 3-to 7-year-old children with autism spectrum disorder()()
por: Kikuchi, Mitsuru, et al.
Publicado: (2013)

Decreased ADP-Ribosyl Cyclase Activity in Peripheral Blood Mononuclear Cells from Diabetic Patients with Nephropathy
por: Ohtsuji, Michio, et al.
Publicado: (2008)

Oxytocin Dynamics in the Body and Brain Regulated by the Receptor for Advanced Glycation End-Products, CD38, CD157, and Nicotinamide Riboside
por: Higashida, Haruhiro, et al.
Publicado: (2022)

Anterior Prefrontal Hemodynamic Connectivity in Conscious 3- to 7-Year-Old Children with Typical Development and Autism Spectrum Disorder
por: Kikuchi, Mitsuru, et al.
Publicado: (2013)

Intestinal transepithelial permeability of oxytocin into the blood is dependent on the receptor for advanced glycation end products in mice
por: Higashida, Haruhiro, et al.
Publicado: (2017)

CD38, CD157, and RAGE as Molecular Determinants for Social Behavior
por: Higashida, Haruhiro, et al.
Publicado: (2019)

Atypical brain lateralisation in the auditory cortex and language performance in 3- to 7-year-old children with high-functioning autism spectrum disorder: a child-customised magnetoencephalography (MEG) study
por: Yoshimura, Yuko, et al.
Publicado: (2013)

A custom magnetoencephalography device reveals brain connectivity and high reading/decoding ability in children with autism
por: Kikuchi, Mitsuru, et al.
Publicado: (2013)

Synonymous nucleotide changes drive papillomavirus evolution
por: King, Kelly M., et al.
Publicado: (2022)

Autism, oxytocin and interoception
por: Quattrocki, E., et al.
Publicado: (2014)

Attenuated relationship between salivary oxytocin levels and attention to social information in adolescents and adults with autism spectrum disorder: a comparative study
por: Fujioka, T., et al.
Publicado: (2020)

Communication Impairment in Ultrasonic Vocal Repertoire during the Suckling Period of Cd157 Knockout Mice: Transient Improvement by Oxytocin
por: Lopatina, Olga L., et al.
Publicado: (2017)

Competitiveness and individual characteristics: a double-blind placebo-controlled study using oxytocin
por: Kurokawa, Hirofumi, et al.
Publicado: (2020)

Long-term oxytocin administration improves social behaviors in a girl with autistic disorder
por: Kosaka, Hirotaka, et al.
Publicado: (2012)

Sex Differences in Salivary Oxytocin and Cortisol Concentration Changes during Cooking in a Small Group
por: Yuhi, Teruko, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qjg8lpmnt2oircd7oq59imjalm