Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation

BACKGROUND: Smchd1 is an epigenetic modifier essential for X chromosome inactivation: female embryos lacking Smchd1 fail during midgestational development. Male mice are less affected by Smchd1-loss, with some (but not all) surviving to become fertile adults on the FVB/n genetic background. On other...

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Detalles Bibliográficos
Autores principales: Mould, Arne W, Pang, Zhenyi, Pakusch, Miha, Tonks, Ian D, Stark, Mitchell, Carrie, Dianne, Mukhopadhyay, Pamela, Seidel, Annica, Ellis, Jonathan J, Deakin, Janine, Wakefield, Matthew J, Krause, Lutz, Blewitt, Marnie E, Kay, Graham F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707822/
https://www.ncbi.nlm.nih.gov/pubmed/23819640
http://dx.doi.org/10.1186/1756-8935-6-19

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