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The Host-Encoded Heme Regulated Inhibitor (HRI) Facilitates Virulence-Associated Activities of Bacterial Pathogens
Here we show that cells lacking the heme-regulated inhibitor (HRI) are highly resistant to infection by bacterial pathogens. By examining the infection process in wild-type and HRI null cells, we found that HRI is required for pathogens to execute their virulence-associated cellular activities. Spec...
Autores principales: | Shrestha, Niraj, Boucher, Justin, Bahnan, Wael, Clark, Emily S., Rosqvist, Roland, Fields, Kenneth A., Khan, Wasif N., Schesser, Kurt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707855/ https://www.ncbi.nlm.nih.gov/pubmed/23874749 http://dx.doi.org/10.1371/journal.pone.0068754 |
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