A Dual-Mode Surface Display System for the Maturation and Production of Monoclonal Antibodies in Glyco-Engineered Pichia pastoris

State-of-the-art monoclonal antibody (mAb) discovery methods that utilize surface display techniques in prokaryotic and eukaryotic cells require multiple steps of reformatting and switching of hosts to transition from display to expression. This results in a separation between antibody affinity matu...

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Detalles Bibliográficos
Autores principales: Shaheen, Hussam H., Prinz, Bianka, Chen, Ming-Tang, Pavoor, Tej, Lin, Song, Houston-Cummings, Nga Rewa, Moore, Renee, Stadheim, Terrance A., Zha, Dongxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707868/
https://www.ncbi.nlm.nih.gov/pubmed/23875020
http://dx.doi.org/10.1371/journal.pone.0070190

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