Cargando…

Anti-Metastatic and Anti-Tumor Growth Effects of Origanum majorana on Highly Metastatic Human Breast Cancer Cells: Inhibition of NFκB Signaling and Reduction of Nitric Oxide Production

BACKGROUND: We have recently reported that Origanum majorana exhibits anticancer activity by promoting cell cycle arrest and apoptosis of the metastatic MDA-MB-231 breast cancer cell line. Here, we extended our study by investigating the effect of O . majorana on the migration, invasion and tumor gr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Al Dhaheri, Yusra, Attoub, Samir, Arafat, Kholoud, AbuQamar, Synan, Viallet, Jean, Saleh, Alaaeldin, Al Agha, Hala, Eid, Ali, Iratni, Rabah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707896/ https://www.ncbi.nlm.nih.gov/pubmed/23874773 http://dx.doi.org/10.1371/journal.pone.0068808

Ejemplares similares

Mitotic Arrest and Apoptosis in Breast Cancer Cells Induced by Origanum majorana Extract: Upregulation of TNF-α and Downregulation of Survivin and Mutant p53
por: Al Dhaheri, Yusra, et al.
Publicado: (2013)

Carnosol Induces ROS-Mediated Beclin1-Independent Autophagy and Apoptosis in Triple Negative Breast Cancer
por: Al Dhaheri, Yusra, et al.
Publicado: (2014)

Rhus coriaria increases protein ubiquitination, proteasomal degradation and triggers non-canonical Beclin-1-independent autophagy and apoptotic cell death in colon cancer cells
por: Athamneh, Khawlah, et al.
Publicado: (2017)

Rhus coriaria suppresses angiogenesis, metastasis and tumor growth of breast cancer through inhibition of STAT3, NFκB and nitric oxide pathways
por: El Hasasna, Hussain, et al.
Publicado: (2016)

Origanum majorana Ethanolic Extract Promotes Colorectal Cancer Cell Death by Triggering Abortive Autophagy and Activation of the Extrinsic Apoptotic Pathway
por: Benhalilou, Nehla, et al.
Publicado: (2019)

PTC-209 Anti-Cancer Effects Involved the Inhibition of STAT3 Phosphorylation
por: Sulaiman, Shahrazad, et al.
Publicado: (2019)

Inhibitory Effects of Salinomycin on Cell Survival, Colony Growth, Migration, and Invasion of Human Non-Small Cell Lung Cancer A549 and LNM35: Involvement of NAG-1
por: Arafat, Kholoud, et al.
Publicado: (2013)

Origanum majorana Essential Oil Triggers p38 MAPK-Mediated Protective Autophagy, Apoptosis, and Caspase-Dependent Cleavage of P70S6K in Colorectal Cancer Cells
por: Athamneh, Khawlah, et al.
Publicado: (2020)

Frondoside A Enhances the Anti-Cancer Effects of Oxaliplatin and 5-Fluorouracil on Colon Cancer Cells
por: Attoub, Samir, et al.
Publicado: (2018)

Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation
por: El Hasasna, Hussain, et al.
Publicado: (2015)

Carnosol, a Natural Polyphenol, Inhibits Migration, Metastasis, and Tumor Growth of Breast Cancer via a ROS-Dependent Proteasome Degradation of STAT3
por: Alsamri, Halima, et al.
Publicado: (2019)

Identification of Arabidopsis Candidate Genes in Response to Biotic and Abiotic Stresses Using Comparative Microarrays
por: Sham, Arjun, et al.
Publicado: (2015)

Microarray analysis of Arabidopsis WRKY33 mutants in response to the necrotrophic fungus Botrytis cinerea
por: Sham, Arjun, et al.
Publicado: (2017)

Targeting Triple-Negative Breast Cancer by the Phytopolyphenol Carnosol: ROS-Dependent Mechanisms
por: Alsamri, Halima, et al.
Publicado: (2023)

Metatranscriptomic Analysis of Multiple Environmental Stresses Identifies RAP2.4 Gene Associated with Arabidopsis Immunity to Botrytis cinerea
por: Sham, Arjun, et al.
Publicado: (2019)

Cytotoxicity and anti-Sporothrix brasiliensis activity of the Origanum majorana Linn. oil
por: Waller, Stefanie Bressan, et al.
Publicado: (2016)

Transcriptome Analysis Reveals Genes Commonly Induced by Botrytis cinerea Infection, Cold, Drought and Oxidative Stresses in Arabidopsis
por: Sham, Arjun, et al.
Publicado: (2014)

Streptomyces globosus UAE1, a Potential Effective Biocontrol Agent for Black Scorch Disease in Date Palm Plantations
por: Saeed, Esam E., et al.
Publicado: (2017)

Propolis: A Detailed Insight of Its Anticancer Molecular Mechanisms
por: Altabbal, Suhib, et al.
Publicado: (2023)

Detection and Management of Mango Dieback Disease in the United Arab Emirates
por: Saeed, Esam Eldin, et al.
Publicado: (2017)

Origanum majorana L.: A Nutritional Supplement With Immunomodulatory Effects
por: Wang, Senye, et al.
Publicado: (2021)

Anti-Hypolipidemic and Anti-Oxidative Effects of Hydroalcoholic Extract of Origanum majorana on the Hepatosteatosis Induced with High-Fat Diet in Rats
por: Pasavei, Abdolmomen Ghaeni, et al.
Publicado: (2020)

The complete chloroplast genome sequence of Origanum majorana L
por: Yen, Le Thi, et al.
Publicado: (2021)

Optimization of ultrasonic-assisted extraction of polyphenols from the polyherbal formulation of Cinnamomum verum, Origanum majorana, and Origanum vulgare and their anti-diabetic capacity in zebrafish (Danio rerio)
por: Pérez Gutiérrez, Rosa Martha, et al.
Publicado: (2021)

Antioxidant and Anti-Inflammatory Effects of Origanum majorana L. Methanolic Extract on Bile Duct Ligation in Male Rats
por: Gheitasi, Izadpanah, et al.
Publicado: (2021)

Effects of altitudes on secondary metabolite contents of Origanum majorana L.
por: Öner, Emel Karaca, et al.
Publicado: (2023)

Effects of Origanum majorana on Breast Cancer Cells: An Alternative to Chemotherapy?
por: Sanders, Zoe, et al.
Publicado: (2023)

Origanum syriacum L. Attenuates the Malignant Phenotype of MDA-MB231 Breast Cancer Cells
por: AlKahlout, Amal, et al.
Publicado: (2022)

Ziziphus nummularia Attenuates the Malignant Phenotype of Human Pancreatic Cancer Cells: Role of ROS
por: Mesmar, Joelle, et al.
Publicado: (2021)

Carnosol Is a Novel Inhibitor of p300 Acetyltransferase in Breast Cancer
por: Alsamri, Halima, et al.
Publicado: (2021)

Anticancer, antioxidant, and antibacterial effects of nanoemulsion of Origanum majorana essential oil
por: Rasti, Fatemeh, et al.
Publicado: (2023)

Assessing the Ameliorative Effect of Selenium Cinnamomum verum, Origanum majorana, and Origanum vulgare Nanoparticles in Diabetic Zebrafish (Danio rerio)
por: Pérez Gutiérrez, Rosa Martha, et al.
Publicado: (2022)

EPAC in Vascular Smooth Muscle Cells
por: Wehbe, Nadine, et al.
Publicado: (2020)

Butein and Frondoside-A Combination Exhibits Additive Anti-Cancer Effects on Tumor Cell Viability, Colony Growth, and Invasion and Synergism on Endothelial Cell Migration
por: Sulaiman, Shahrazad, et al.
Publicado: (2021)

Antifungal and Anti-Virulent Activity of Origanum majorana L. Essential Oil on Candida albicans and In Vivo Toxicity in the Galleria mellonella Larval Model
por: Kaskatepe, Banu, et al.
Publicado: (2022)

Origanum majorana Attenuates Nephrotoxicity of Cisplatin Anticancer Drug through Ameliorating Oxidative Stress
por: Soliman, Amel M., et al.
Publicado: (2016)

Origanum majorana Essential Oil Lacks Mutagenic Activity in the Salmonella/Microsome and Micronucleus Assays
por: Dantas, Andrea dos Santos, et al.
Publicado: (2016)

A Study on the Phytotoxic Potential of the Seasoning Herb Marjoram (Origanum majorana L.) Leaves
por: Cala, Antonio, et al.
Publicado: (2021)

Origanum majorana Essential Oil—A Review of Its Chemical Profile and Pesticide Activity
por: Kakouri, Eleni, et al.
Publicado: (2022)

The efficacy of Origanum majorana nanocubosomal systems in ameliorating submandibular salivary gland alterations in streptozotocin-induced diabetic rats
por: Farag, Dina B. E., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1u0mbs4j36046i03rf8jik3lbg