Inhibition of β2-Microglobulin/Hemochromatosis Enhances Radiation Sensitivity by Induction of Iron Overload in Prostate Cancer Cells

BACKGROUND: Bone metastasis is the most lethal form of several cancers. The β2-microglobulin (β2-M)/hemochromatosis (HFE) complex plays an important role in cancer development and bone metastasis. We demonstrated previously that overexpression of β2-M in prostate, breast, lung and renal cancer leads...

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Detalles Bibliográficos
Autores principales: Josson, Sajni, Matsuoka, Yasuhiro, Gururajan, Murali, Nomura, Takeo, Huang, Wen-Chin, Yang, Xiaojian, Lin, Jin-tai, Bridgman, Roger, Chu, Chia-Yi, Johnstone, Peter A., Zayzafoon, Majd, Hu, Peizhen, Zhau, Haiyen, Berel, Dror, Rogatko, Andre, Chung, Leland W. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707913/
https://www.ncbi.nlm.nih.gov/pubmed/23874600
http://dx.doi.org/10.1371/journal.pone.0068366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707913/
https://www.ncbi.nlm.nih.gov/pubmed/23874600
http://dx.doi.org/10.1371/journal.pone.0068366

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