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Evolution of the Plasma and Tissue Kallikreins, and Their Alternative Splicing Isoforms

Kallikreins are secreted serine proteases with important roles in human physiology. Human plasma kallikrein, encoded by the KLKB1 gene on locus 4q34-35, functions in the blood coagulation pathway, and in regulating blood pressure. The human tissue kallikrein and kallikrein-related peptidases (KLKs)...

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Detalles Bibliográficos
Autores principales: Koumandou, Vassiliki Lila, Scorilas, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707919/
https://www.ncbi.nlm.nih.gov/pubmed/23874499
http://dx.doi.org/10.1371/journal.pone.0068074