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Characterization of Chromosome Stability in Diploid, Polyploid and Hybrid Yeast Cells

Chromosome instability is a key component of cancer progression and many heritable diseases. Understanding why some chromosomes are more unstable than others could provide insight into understanding genome integrity. Here we systematically investigate the spontaneous chromosome loss for all sixteen...

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Detalles Bibliográficos
Autores principales: Kumaran, Rajaraman, Yang, Shi-Yow, Leu, Jun-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707968/
https://www.ncbi.nlm.nih.gov/pubmed/23874507
http://dx.doi.org/10.1371/journal.pone.0068094