Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?

The insulin-like growth factor-2 mRNA-binding proteins 1, 2, and 3 (IGF2BP1, IGF2BP2, IGF2BP3) belong to a conserved family of RNA-binding, oncofetal proteins. Several studies have shown that these proteins act in various important aspects of cell function, such as cell polarization, migration, morp...

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Detalles Bibliográficos
Autores principales: Bell, Jessica L., Wächter, Kristin, Mühleck, Britta, Pazaitis, Nikolaos, Köhn, Marcel, Lederer, Marcell, Hüttelmaier, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708292/
https://www.ncbi.nlm.nih.gov/pubmed/23069990
http://dx.doi.org/10.1007/s00018-012-1186-z

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