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Rare Case of Renal Cell Carcinoma with Mandibular Swelling as Primary Presentation
Introduction. Renal cell carcinoma accounts for approximately 3% of adult malignancies and 90–95% of neoplasms arising from the kidney. This disease is characterized by a lack of early warning signs, diverse clinical manifestations, and resistance to radiation and chemotherapy. Approximately one-thi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708429/ https://www.ncbi.nlm.nih.gov/pubmed/23878758 http://dx.doi.org/10.1155/2013/806192 |
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author | Jallu, Aleena Latoo, Manzoor Pampori, Rafiq |
author_facet | Jallu, Aleena Latoo, Manzoor Pampori, Rafiq |
author_sort | Jallu, Aleena |
collection | PubMed |
description | Introduction. Renal cell carcinoma accounts for approximately 3% of adult malignancies and 90–95% of neoplasms arising from the kidney. This disease is characterized by a lack of early warning signs, diverse clinical manifestations, and resistance to radiation and chemotherapy. Approximately one-third of patients with renal cell carcinoma have metastatic disease at initial presentation. Fifteen percent of patients with renal cell carcinoma are said to present with metastases in the head and neck region. Most of the metastases from RCC to the head and neck involve the thyroid gland. The head and neck are unusual sites for metastases, but skin, skeletal muscle, thyroid gland, nasal cavity and paranasal sinus metastases have been reported. Case Report. The following report describes a rare case where the patient presented with mandibular swelling of short duration as the primary complaint without any symptom or sign pertaining to urinary tract and was found to have renal cell carcinoma on further workup. Conclusion. Metastatic renal cell carcinoma is a diagnostic dilemma especially when there is no pointer historically towards renal cell carcinoma as was in our case. An unusual vascular osteolytic lesion in head and neck in a middle-aged person should be dealt with high index of suspicion with renal cell carcinoma at the back of the mind. |
format | Online Article Text |
id | pubmed-3708429 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-37084292013-07-22 Rare Case of Renal Cell Carcinoma with Mandibular Swelling as Primary Presentation Jallu, Aleena Latoo, Manzoor Pampori, Rafiq Case Rep Urol Case Report Introduction. Renal cell carcinoma accounts for approximately 3% of adult malignancies and 90–95% of neoplasms arising from the kidney. This disease is characterized by a lack of early warning signs, diverse clinical manifestations, and resistance to radiation and chemotherapy. Approximately one-third of patients with renal cell carcinoma have metastatic disease at initial presentation. Fifteen percent of patients with renal cell carcinoma are said to present with metastases in the head and neck region. Most of the metastases from RCC to the head and neck involve the thyroid gland. The head and neck are unusual sites for metastases, but skin, skeletal muscle, thyroid gland, nasal cavity and paranasal sinus metastases have been reported. Case Report. The following report describes a rare case where the patient presented with mandibular swelling of short duration as the primary complaint without any symptom or sign pertaining to urinary tract and was found to have renal cell carcinoma on further workup. Conclusion. Metastatic renal cell carcinoma is a diagnostic dilemma especially when there is no pointer historically towards renal cell carcinoma as was in our case. An unusual vascular osteolytic lesion in head and neck in a middle-aged person should be dealt with high index of suspicion with renal cell carcinoma at the back of the mind. Hindawi Publishing Corporation 2013 2013-06-25 /pmc/articles/PMC3708429/ /pubmed/23878758 http://dx.doi.org/10.1155/2013/806192 Text en Copyright © 2013 Aleena Jallu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Jallu, Aleena Latoo, Manzoor Pampori, Rafiq Rare Case of Renal Cell Carcinoma with Mandibular Swelling as Primary Presentation |
title | Rare Case of Renal Cell Carcinoma with Mandibular Swelling as Primary Presentation |
title_full | Rare Case of Renal Cell Carcinoma with Mandibular Swelling as Primary Presentation |
title_fullStr | Rare Case of Renal Cell Carcinoma with Mandibular Swelling as Primary Presentation |
title_full_unstemmed | Rare Case of Renal Cell Carcinoma with Mandibular Swelling as Primary Presentation |
title_short | Rare Case of Renal Cell Carcinoma with Mandibular Swelling as Primary Presentation |
title_sort | rare case of renal cell carcinoma with mandibular swelling as primary presentation |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708429/ https://www.ncbi.nlm.nih.gov/pubmed/23878758 http://dx.doi.org/10.1155/2013/806192 |
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