Patterns of Epistasis between Beneficial Mutations in an Antibiotic Resistance Gene

Understanding epistasis is central to biology. For instance, epistatic interactions determine the topography of the fitness landscape and affect the dynamics and determinism of adaptation. However, few empirical data are available, and comparing results is complicated by confounding variation in the...

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Detalles Bibliográficos
Autores principales: Schenk, Martijn F., Szendro, Ivan G., Salverda, Merijn L.M., Krug, Joachim, de Visser, J. Arjan G.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708503/
https://www.ncbi.nlm.nih.gov/pubmed/23676768
http://dx.doi.org/10.1093/molbev/mst096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708503/
https://www.ncbi.nlm.nih.gov/pubmed/23676768
http://dx.doi.org/10.1093/molbev/mst096

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