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Patterns of Epistasis between Beneficial Mutations in an Antibiotic Resistance Gene
Understanding epistasis is central to biology. For instance, epistatic interactions determine the topography of the fitness landscape and affect the dynamics and determinism of adaptation. However, few empirical data are available, and comparing results is complicated by confounding variation in the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708503/ https://www.ncbi.nlm.nih.gov/pubmed/23676768 http://dx.doi.org/10.1093/molbev/mst096 |