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Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma

BACKGROUND: Autophagy is a lysosomal degradation pathway that can provide energy through its recycling mechanism to act as a cytoprotective adaptive response mediating treatment resistance in cancer cells. We investigated the autophagy-inducing effects of ZD6474, a small-molecule inhibitor that bloc...

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Detalles Bibliográficos
Autores principales:	Shen, J, Zheng, H, Ruan, J, Fang, W, Li, A, Tian, G, Niu, X, Luo, S, Zhao, P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708568/ https://www.ncbi.nlm.nih.gov/pubmed/23799852 http://dx.doi.org/10.1038/bjc.2013.306

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