Hypoxia regulates FGFR3 expression via HIF-1α and miR-100 and contributes to cell survival in non-muscle invasive bladder cancer

BACKGROUND: Non-muscle invasive (NMI) bladder cancer is characterised by increased expression and activating mutations of FGFR3. We have previously investigated the role of microRNAs in bladder cancer and have shown that FGFR3 is a target of miR-100. In this study, we investigated the effects of hyp...

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Detalles Bibliográficos
Autores principales: Blick, C, Ramachandran, A, Wigfield, S, McCormick, R, Jubb, A, Buffa, F M, Turley, H, Knowles, M A, Cranston, D, Catto, J, Harris, A L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708569/
https://www.ncbi.nlm.nih.gov/pubmed/23778527
http://dx.doi.org/10.1038/bjc.2013.240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708569/
https://www.ncbi.nlm.nih.gov/pubmed/23778527
http://dx.doi.org/10.1038/bjc.2013.240

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