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IRF-1 responsiveness to IFN-γ predicts different cancer immune phenotypes

BACKGROUND: Several lines of evidence suggest a dichotomy between immune active and quiescent cancers, with the former associated with a good prognostic phenotype and better responsiveness to immunotherapy. Central to such dichotomy is the master regulator of the acute inflammatory process interfero...

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Detalles Bibliográficos
Autores principales:	Murtas, D, Maric, D, De Giorgi, V, Reinboth, J, Worschech, A, Fetsch, P, Filie, A, Ascierto, M L, Bedognetti, D, Liu, Q, Uccellini, L, Chouchane, L, Wang, E, Marincola, F M, Tomei, S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708578/ https://www.ncbi.nlm.nih.gov/pubmed/23807161 http://dx.doi.org/10.1038/bjc.2013.335

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