Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function

Phagocytosis is a fundamental cellular process that is pivotal for immunity as it coordinates microbial killing, innate immune activation and antigen presentation. An essential step in this process is phagosome acidification, which regulates a number of functions of these organelles that allow them...

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Detalles Bibliográficos
Autores principales: Sokolovska, Anna, Becker, Christine E., Eddie Ip, WK, Rathinam, Vijay A.K., Brudner, Matthew, Paquette, Nicholas, Tanne, Antoine, Vanaja, Sivapriya K., Moore, Kathryn J., Fitzgerald, Katherine A., Lacy-Hulbert, Adam, Stuart, Lynda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708594/
https://www.ncbi.nlm.nih.gov/pubmed/23644505
http://dx.doi.org/10.1038/ni.2595

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