Corticosteroid Induced, HHV-8 Positive Kaposi’s Sarcoma in a Non-HIV Elderly Patient

Kaposi’s sarcoma (KS) was first described in 1872 by Moritz Kaposi. In 1994, Chang et al. first identified DNA sequences corresponding to human herpesvirus-8 (HHV-8) in AIDS-associated Kaposi sarcoma biopsies. It is now believed that presence of HHV-8 is necessary but not sufficient to cause KS. Oth...

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Detalles Bibliográficos
Autores principales: Wani, Gh Mohiuddin, Ahmad, Sheikh Manzoor, Qayoom, Seema, Khursheed, Bilquees, Khan, A.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Islamic Medical Association of North America 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708632/
https://www.ncbi.nlm.nih.gov/pubmed/23864989
http://dx.doi.org/10.5915/44-1-9317
Descripción
Sumario:Kaposi’s sarcoma (KS) was first described in 1872 by Moritz Kaposi. In 1994, Chang et al. first identified DNA sequences corresponding to human herpesvirus-8 (HHV-8) in AIDS-associated Kaposi sarcoma biopsies. It is now believed that presence of HHV-8 is necessary but not sufficient to cause KS. Other factors like immunosuppressive therapy also play a role. We describe an HIV-negative elderly patient who developed KS of skin and mucous membrane after prolonged use of corticosteroids for knee pain. The patient was positive for HHV-8.

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