Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice

BACKGROUND: Glaucoma is an age-related neurodegenerative disorder involving the loss of retinal ganglion cells (RGCs), which results in blindness. Studies in animal models have shown that activation of inflammatory processes occurs early in the disease. In particular, the complement cascade is activ...

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Detalles Bibliográficos
Autores principales: Howell, Gareth R, Soto, Ileana, Ryan, Margaret, Graham, Leah C, Smith, Richard S, John, Simon WM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708765/
https://www.ncbi.nlm.nih.gov/pubmed/23806181
http://dx.doi.org/10.1186/1742-2094-10-76

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