Cargando…
Gene Set Signature of Reversal Reaction Type I in Leprosy Patients
Leprosy reversal reactions type 1 (T1R) are acute immune episodes that affect a subset of leprosy patients and remain a major cause of nerve damage. Little is known about the relative importance of innate versus environmental factors in the pathogenesis of T1R. In a retrospective design, we evaluate...
Autores principales: | Orlova, Marianna, Cobat, Aurélie, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Van Thuc, Nguyen, Spencer, John, Nédélec, Yohann, Barreiro, Luis, Thai, Vu Hong, Abel, Laurent, Alcaïs, Alexandre, Schurr, Erwin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708838/ https://www.ncbi.nlm.nih.gov/pubmed/23874223 http://dx.doi.org/10.1371/journal.pgen.1003624 |
Ejemplares similares
-
Pauci- and Multibacillary Leprosy: Two Distinct, Genetically Neglected Diseases
por: Gaschignard, Jean, et al.
Publicado: (2016) -
A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy
por: Fava, Vinicius M., et al.
Publicado: (2016) -
Deep resequencing identifies candidate functional genes in leprosy GWAS loci
por: Fava, Vinicius M., et al.
Publicado: (2021) -
The complex pattern of genetic associations of leprosy with HLA class I and class II alleles can be reduced to four amino acid positions
por: Dallmann-Sauer, Monica, et al.
Publicado: (2020) -
PARK2 Mediates Interleukin 6 and Monocyte Chemoattractant Protein 1 Production by Human Macrophages
por: de Léséleuc, Louis, et al.
Publicado: (2013)