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Reprogramming of Murine Macrophages through TLR2 Confers Viral Resistance via TRAF3-Mediated, Enhanced Interferon Production

The cell surface/endosomal Toll-like Receptors (TLRs) are instrumental in initiating immune responses to both bacteria and viruses. With the exception of TLR2, all TLRs and cytosolic RIG-I-like receptors (RLRs) with known virus-derived ligands induce type I interferons (IFNs) in macrophages or dendr...

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Detalles Bibliográficos
Autores principales:	Perkins, Darren J., Polumuri, Swamy K., Pennini, Meghan E., Lai, Wendy, Xie, Ping, Vogel, Stefanie N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708851/ https://www.ncbi.nlm.nih.gov/pubmed/23853595 http://dx.doi.org/10.1371/journal.ppat.1003479

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