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Distinct Allelic Patterns of Nanog Expression Impart Embryonic Stem Cell Population Heterogeneity
Nanog is a principal pluripotency regulator exhibiting a disperse distribution within stem cell populations in vivo and in vitro. Increasing evidence points to a functional role of Nanog heterogeneity on stem cell fate decisions. Allelic control of Nanog gene expression was reported recently in mous...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708867/ https://www.ncbi.nlm.nih.gov/pubmed/23874182 http://dx.doi.org/10.1371/journal.pcbi.1003140 |