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Association between HSP90 and Her2 in Gastric and Gastroesophageal Carcinomas

BACKGROUND: Her2 expression and amplification occurs in a significant subset of gastro-esophageal carcinomas. Her2 is a client protein of molecular chaperones, e.g. heat shock protein (HSP) 90, rendering targeted therapies against Her2/HSP90 an interesting approach. This study aimed to investigate t...

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Detalles Bibliográficos
Autores principales: Berezowska, Sabina, Novotny, Alexander, Bauer, Karina, Feuchtinger, Annette, Slotta-Huspenina, Julia, Becker, Karen, Langer, Rupert, Walch, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708885/
https://www.ncbi.nlm.nih.gov/pubmed/23874879
http://dx.doi.org/10.1371/journal.pone.0069098