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Inhibition of PbGP43 Expression May Suggest that gp43 is a Virulence Factor in Paracoccidioides brasiliensis

Glycoprotein gp43 is an immunodominant diagnostic antigen for paracoccidioidomycosis caused by Paracoccidioides brasiliensis. It is abundantly secreted in isolates such as Pb339. It is structurally related to beta-1,3-exoglucanases, however inactive. Its function in fungal biology is unknown, but it...

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Detalles Bibliográficos
Autores principales:	Torres, Isaura, Hernandez, Orville, Tamayo, Diana, Muñoz, Jose F., Leitão, Natanael P., García, Ana M., Restrepo, Angela, Puccia, Rosana, McEwen, Juan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708949/ https://www.ncbi.nlm.nih.gov/pubmed/23874627 http://dx.doi.org/10.1371/journal.pone.0068434

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