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Cholesterol-Secreting and Statin-Responsive Hepatocytes from Human ES and iPS Cells to Model Hepatic Involvement in Cardiovascular Health

Hepatocytes play a central and crucial role in cholesterol and lipid homeostasis, and their proper function is of key importance for cardiovascular health. In particular, hepatocytes (especially periportal hepatocytes) endogenously synthesize large amounts of cholesterol and secrete it into circulat...

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Detalles Bibliográficos
Autores principales:	Krueger, Winfried H., Tanasijevic, Borko, Barber, Vanessa, Flamier, Anthony, Gu, Xinsheng, Manautou, Jose, Rasmussen, Theodore P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708950/ https://www.ncbi.nlm.nih.gov/pubmed/23874411 http://dx.doi.org/10.1371/journal.pone.0067296

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