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CCN2/CTGF is required for matrix organization and to protect growth plate chondrocytes from cellular stress

CCN2 (connective tissue growth factor (CTGF/CCN2)) is a matricellular protein that utilizes integrins to regulate cell proliferation, migration and survival. The loss of CCN2 leads to perinatal lethality resulting from a severe chondrodysplasia. Upon closer inspection of Ccn2 mutant mice, we observe...

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Detalles Bibliográficos
Autores principales:	Hall-Glenn, Faith, Aivazi, Armen, Akopyan, Lusi, Ong, Jessica R., Baxter, Ruth R., Benya, Paul D., Goldschmeding, Roel, van Nieuwenhoven, Frans A., Hunziker, Ernst B., Lyons, Karen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709047/ https://www.ncbi.nlm.nih.gov/pubmed/23666466 http://dx.doi.org/10.1007/s12079-013-0201-y

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