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Intranasal Insulin as a Treatment for Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence
Research in animals and humans has associated Alzheimer’s disease (AD) with decreased cerebrospinal fluid levels of insulin in combination with decreased insulin sensitivity (insulin resistance) in the brain. This phenomenon is accompanied by attenuated receptor expression of insulin and insulin-lik...
Autores principales: | Freiherr, Jessica, Hallschmid, Manfred, Frey, William H., Brünner, Yvonne F., Chapman, Colin D., Hölscher, Christian, Craft, Suzanne, De Felice, Fernanda G., Benedict, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709085/ https://www.ncbi.nlm.nih.gov/pubmed/23719722 http://dx.doi.org/10.1007/s40263-013-0076-8 |
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