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Comparing the neural correlates of affective and cognitive theory of mind using fMRI: Involvement of the basal ganglia in affective theory of mind

Theory of Mind (ToM) is the ability to infer other people’s mental states like intentions or desires. ToM can be differentiated into affective (i.e., recognizing the feelings of another person) and cognitive (i.e., inferring the mental state of the counterpart) subcomponents. Recently, subcortical s...

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Autores principales: Bodden, Maren E., Kübler, Dorothee, Knake, Susanne, Menzler, Katja, Heverhagen, Johannes T., Sommer, Jens, Kalbe, Elke, Krach, Sören, Dodel, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: University of Finance and Management in Warsaw 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709103/
https://www.ncbi.nlm.nih.gov/pubmed/23853676
http://dx.doi.org/10.2478/v10053-008-0129-6
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author Bodden, Maren E.
Kübler, Dorothee
Knake, Susanne
Menzler, Katja
Heverhagen, Johannes T.
Sommer, Jens
Kalbe, Elke
Krach, Sören
Dodel, Richard
author_facet Bodden, Maren E.
Kübler, Dorothee
Knake, Susanne
Menzler, Katja
Heverhagen, Johannes T.
Sommer, Jens
Kalbe, Elke
Krach, Sören
Dodel, Richard
author_sort Bodden, Maren E.
collection PubMed
description Theory of Mind (ToM) is the ability to infer other people’s mental states like intentions or desires. ToM can be differentiated into affective (i.e., recognizing the feelings of another person) and cognitive (i.e., inferring the mental state of the counterpart) subcomponents. Recently, subcortical structures such as the basal ganglia (BG) have also been ascribed to the multifaceted concept ToM and most BG disorders have been reported to elicit ToM deficits. In order to assess both the correlates of affective and cognitive ToM as well as involvement of the basal ganglia, 30 healthy participants underwent event-related fMRI scanning, neuropsychological testing, and filled in questionnaires concerning different aspects of ToM and empathy. Directly contrasting affective (aff) as well as cognitive (cog) ToM to the control (phy) condition, activation was found in classical ToM regions, namely parts of the temporal lobe including the superior temporal sulcus, the supplementary motor area, and parietal structures in the right hemisphere. The contrast aff > phy yielded additional activation in the orbitofrontal cortex on the right and the cingulate cortex, the precentral and inferior frontal gyrus and the cerebellum on the left. The right BG were recruited in this contrast as well. The direct contrast aff > cog showed activation in the temporoparietal junction and the cingulate cortex on the right as well as in the left supplementary motor area. The reverse contrast cog > aff however did not yield any significant clusters. In summary, affective and cognitive ToM partly share neural correlates but can also be differentiated anatomically. Furthermore, the BG are involved in affective ToM and thus their contribution is discussed as possibly providing a motor component of simulation processes, particularly in affective ToM.
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spelling pubmed-37091032013-07-12 Comparing the neural correlates of affective and cognitive theory of mind using fMRI: Involvement of the basal ganglia in affective theory of mind Bodden, Maren E. Kübler, Dorothee Knake, Susanne Menzler, Katja Heverhagen, Johannes T. Sommer, Jens Kalbe, Elke Krach, Sören Dodel, Richard Adv Cogn Psychol Research Article Theory of Mind (ToM) is the ability to infer other people’s mental states like intentions or desires. ToM can be differentiated into affective (i.e., recognizing the feelings of another person) and cognitive (i.e., inferring the mental state of the counterpart) subcomponents. Recently, subcortical structures such as the basal ganglia (BG) have also been ascribed to the multifaceted concept ToM and most BG disorders have been reported to elicit ToM deficits. In order to assess both the correlates of affective and cognitive ToM as well as involvement of the basal ganglia, 30 healthy participants underwent event-related fMRI scanning, neuropsychological testing, and filled in questionnaires concerning different aspects of ToM and empathy. Directly contrasting affective (aff) as well as cognitive (cog) ToM to the control (phy) condition, activation was found in classical ToM regions, namely parts of the temporal lobe including the superior temporal sulcus, the supplementary motor area, and parietal structures in the right hemisphere. The contrast aff > phy yielded additional activation in the orbitofrontal cortex on the right and the cingulate cortex, the precentral and inferior frontal gyrus and the cerebellum on the left. The right BG were recruited in this contrast as well. The direct contrast aff > cog showed activation in the temporoparietal junction and the cingulate cortex on the right as well as in the left supplementary motor area. The reverse contrast cog > aff however did not yield any significant clusters. In summary, affective and cognitive ToM partly share neural correlates but can also be differentiated anatomically. Furthermore, the BG are involved in affective ToM and thus their contribution is discussed as possibly providing a motor component of simulation processes, particularly in affective ToM. University of Finance and Management in Warsaw 2013-03-15 /pmc/articles/PMC3709103/ /pubmed/23853676 http://dx.doi.org/10.2478/v10053-008-0129-6 Text en Copyright: © 2013 University of Finance and Management in Warsaw http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Bodden, Maren E.
Kübler, Dorothee
Knake, Susanne
Menzler, Katja
Heverhagen, Johannes T.
Sommer, Jens
Kalbe, Elke
Krach, Sören
Dodel, Richard
Comparing the neural correlates of affective and cognitive theory of mind using fMRI: Involvement of the basal ganglia in affective theory of mind
title Comparing the neural correlates of affective and cognitive theory of mind using fMRI: Involvement of the basal ganglia in affective theory of mind
title_full Comparing the neural correlates of affective and cognitive theory of mind using fMRI: Involvement of the basal ganglia in affective theory of mind
title_fullStr Comparing the neural correlates of affective and cognitive theory of mind using fMRI: Involvement of the basal ganglia in affective theory of mind
title_full_unstemmed Comparing the neural correlates of affective and cognitive theory of mind using fMRI: Involvement of the basal ganglia in affective theory of mind
title_short Comparing the neural correlates of affective and cognitive theory of mind using fMRI: Involvement of the basal ganglia in affective theory of mind
title_sort comparing the neural correlates of affective and cognitive theory of mind using fmri: involvement of the basal ganglia in affective theory of mind
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709103/
https://www.ncbi.nlm.nih.gov/pubmed/23853676
http://dx.doi.org/10.2478/v10053-008-0129-6
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