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SULT2A1 Gene Copy Number Variation is Associated with Urinary Excretion Rate of Steroid Sulfates

Human cytosolic sulfotransferases (SULT) 2A1 is the main enzyme involved in the sulfate conjugation of dehydroepiandrosterone, a weak androgen, and the main androgen precursor, whereas estrogens are mainly conjugated by SULT1A1. Here we have identified a copy number variation (CNV) polymorphism in t...

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Detalles Bibliográficos
Autores principales: Schulze, Jenny, Johansson, Maria, Thörngren, John-Olof, Garle, Mats, Rane, Anders, Ekström, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709130/
https://www.ncbi.nlm.nih.gov/pubmed/23874324
http://dx.doi.org/10.3389/fendo.2013.00088