Haemodynamically dependent valvulogenesis of zebrafish heart is mediated by flow-dependent expression of miR-21

Heartbeat is required for normal development of the heart, and perturbation of intracardiac flow leads to morphological defects resembling congenital heart diseases. These observations implicate intracardiac haemodynamics in cardiogenesis, but the signalling cascades connecting physical forces, gene...

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Detalles Bibliográficos
Autores principales: Banjo, Toshihiro, Grajcarek, Janin, Yoshino, Daisuke, Osada, Hideto, Miyasaka, Kota Y., Kida, Yasuyuki S., Ueki, Yosuke, Nagayama, Kazuaki, Kawakami, Koichi, Matsumoto, Takeo, Sato, Masaaki, Ogura, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709480/
https://www.ncbi.nlm.nih.gov/pubmed/23748970
http://dx.doi.org/10.1038/ncomms2978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709480/
https://www.ncbi.nlm.nih.gov/pubmed/23748970
http://dx.doi.org/10.1038/ncomms2978

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