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Seroepidemiology of Hepatitis A in South Korea: A Nationwide Study by the Eone Reference Laboratory

BACKGROUND: We evaluated the recent prevalence of serologic markers of hepatitis A virus (HAV) in South Korea. METHODS: The study data were the results of 60 126 anti-HAV (total) tests and 30 786 anti-HAV IgM tests that were performed during April 2009 through March 2010 by the Eone Reference Labora...

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Autores principales: Cho, Sung Eun, Kim, Youngdae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Epidemiological Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709547/
https://www.ncbi.nlm.nih.gov/pubmed/23629647
http://dx.doi.org/10.2188/jea.JE20120188
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author Cho, Sung Eun
Kim, Youngdae
author_facet Cho, Sung Eun
Kim, Youngdae
author_sort Cho, Sung Eun
collection PubMed
description BACKGROUND: We evaluated the recent prevalence of serologic markers of hepatitis A virus (HAV) in South Korea. METHODS: The study data were the results of 60 126 anti-HAV (total) tests and 30 786 anti-HAV IgM tests that were performed during April 2009 through March 2010 by the Eone Reference Laboratory at the request of 1935 institutions throughout Korea. RESULTS: The overall positivity rate was 51.06% on the anti-HAV (total) test and 11.20% on the anti-HAV IgM test. As compared with the other age groups the rate of anti-HAV (total) positivity was significantly lower (P < 0.001), and the rate of anti-HAV IgM positivity was significantly higher (P < 0.001), among Koreans aged 11 to 40 years. The seroprevalence of anti-HAV IgM significantly differed according to region but not by referral date. CONCLUSIONS: This was the largest nationwide study in South Korea by 1 laboratory, and it provides useful recent baseline data on hepatitis A in Asia. The findings suggest that active immunization of younger Koreans should be made a priority.
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spelling pubmed-37095472013-09-17 Seroepidemiology of Hepatitis A in South Korea: A Nationwide Study by the Eone Reference Laboratory Cho, Sung Eun Kim, Youngdae J Epidemiol Original Article BACKGROUND: We evaluated the recent prevalence of serologic markers of hepatitis A virus (HAV) in South Korea. METHODS: The study data were the results of 60 126 anti-HAV (total) tests and 30 786 anti-HAV IgM tests that were performed during April 2009 through March 2010 by the Eone Reference Laboratory at the request of 1935 institutions throughout Korea. RESULTS: The overall positivity rate was 51.06% on the anti-HAV (total) test and 11.20% on the anti-HAV IgM test. As compared with the other age groups the rate of anti-HAV (total) positivity was significantly lower (P < 0.001), and the rate of anti-HAV IgM positivity was significantly higher (P < 0.001), among Koreans aged 11 to 40 years. The seroprevalence of anti-HAV IgM significantly differed according to region but not by referral date. CONCLUSIONS: This was the largest nationwide study in South Korea by 1 laboratory, and it provides useful recent baseline data on hepatitis A in Asia. The findings suggest that active immunization of younger Koreans should be made a priority. Japan Epidemiological Association 2013-07-05 /pmc/articles/PMC3709547/ /pubmed/23629647 http://dx.doi.org/10.2188/jea.JE20120188 Text en © 2013 Japan Epidemiological Association. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Original Article
Cho, Sung Eun
Kim, Youngdae
Seroepidemiology of Hepatitis A in South Korea: A Nationwide Study by the Eone Reference Laboratory
title Seroepidemiology of Hepatitis A in South Korea: A Nationwide Study by the Eone Reference Laboratory
title_full Seroepidemiology of Hepatitis A in South Korea: A Nationwide Study by the Eone Reference Laboratory
title_fullStr Seroepidemiology of Hepatitis A in South Korea: A Nationwide Study by the Eone Reference Laboratory
title_full_unstemmed Seroepidemiology of Hepatitis A in South Korea: A Nationwide Study by the Eone Reference Laboratory
title_short Seroepidemiology of Hepatitis A in South Korea: A Nationwide Study by the Eone Reference Laboratory
title_sort seroepidemiology of hepatitis a in south korea: a nationwide study by the eone reference laboratory
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709547/
https://www.ncbi.nlm.nih.gov/pubmed/23629647
http://dx.doi.org/10.2188/jea.JE20120188
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