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Deletion of immunomodulator C6 from vaccinia virus strain Western Reserve enhances virus immunogenicity and vaccine efficacy

Vectors based on vaccinia virus (VACV), the vaccine used to eradicate smallpox, are currently popular candidates for the vaccination against numerous infectious diseases including malaria and AIDS. Although VACV induces robust cellular and humoral responses, enhancing the safety and efficacy of thes...

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Detalles Bibliográficos
Autores principales: Sumner, Rebecca P., Ren, Hongwei, Smith, Geoffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709586/
https://www.ncbi.nlm.nih.gov/pubmed/23288427
http://dx.doi.org/10.1099/vir.0.049700-0