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p53 controls hepatitis C virus non-structural protein 5A-mediated downregulation of GADD45α expression via the NF-κB and PI3K–Akt pathways

Growth arrest and DNA-damage-inducible gene 45-α (GADD45α) protein has been shown to be a tumour suppressor and is implicated in cell-cycle arrest and suppression of cell growth. The hepatitis C virus (HCV) non-structural 5A (NS5A) protein plays an important role in cell survival and is linked to th...

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Detalles Bibliográficos
Autores principales:	Cheng, Du, Zhao, Lei, Zhang, Leiliang, Jiang, Yongfang, Tian, Yi, Xiao, Xinqiang, Gong, Guozhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for General Microbiology 2013
Materias:	Animal
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709614/ https://www.ncbi.nlm.nih.gov/pubmed/23114628 http://dx.doi.org/10.1099/vir.0.046052-0

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