Dugbe virus ovarian tumour domain interferes with ubiquitin/ISG15-regulated innate immune cell signalling

The ovarian tumour (OTU) domain of the nairovirus L protein has been shown to remove ubiquitin and interferon-stimulated gene 15 protein (ISG15) from host cell proteins, which is expected to have multiple effects on cell signalling pathways. We have confirmed that the OTU domain from the L protein o...

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Detalles Bibliográficos
Autores principales: Bakshi, S., Holzer, B., Bridgen, A., McMullan, G., Quinn, D. G., Baron, M. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2013
Materias:
Animal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709621/
https://www.ncbi.nlm.nih.gov/pubmed/23136361
http://dx.doi.org/10.1099/vir.0.048322-0

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