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Inhibiting TGFβ1 has a protective effect on mouse bone marrow suppression following ionizing radiation exposure in vitro

Ionizing radiation (IR) causes not only acute tissue damage but also residual bone marrow (BM) suppression. The induction of residual BM injury is primarily attributable to the induction of reactive oxygen species (ROS) pressure in hematopoietic cells. In this study, we examined if SB431542, a trans...

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Detalles Bibliográficos
Autores principales: Zhang, Heng, Wang, Ying-ai, Meng, Aimin, Yan, Hao, Wang, Xinzhuo, Niu, Jingxiu, Li, Jin, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709670/
https://www.ncbi.nlm.nih.gov/pubmed/23370919
http://dx.doi.org/10.1093/jrr/rrs142