Three Dimensional Quantitative Structure-Activity Relationship of 5H-Pyrido[4,3-b]indol-4-carboxamide JAK2 Inhibitors

Janus kinase 2 (JAK2) is an intracellular nonreceptor tyrosine kinase that belongs to the JAK family of kinases, which play an important role in survival, proliferation, and differentiation of a variety of cells. JAK2 inhibitors are potential drugs for the treatment of myeloproliferative neoplasms....

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Detalles Bibliográficos
Autores principales: Wu, Xiaoyun, Wan, Shanhe, Zhang, Jiajie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709772/
https://www.ncbi.nlm.nih.gov/pubmed/23739681
http://dx.doi.org/10.3390/ijms140612037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709772/
https://www.ncbi.nlm.nih.gov/pubmed/23739681
http://dx.doi.org/10.3390/ijms140612037

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