Cargando…

Analysis of Transcriptional Regulation of the Human miR-17-92 Cluster; Evidence for Involvement of Pim-1

The human polycistronic miRNA cluster miR-17-92 is frequently overexpressed in hematopoietic malignancies and cancers. Its transcription is in part controlled by an E2F-regulated host gene promoter. An intronic A/T-rich region directly upstream of the miRNA coding region also contributes to cluster...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thomas, Maren, Lange-Grünweller, Kerstin, Hartmann, Dorothee, Golde, Lara, Schlereth, Julia, Streng, Dennis, Aigner, Achim, Grünweller, Arnold, Hartmann, Roland K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709785/ https://www.ncbi.nlm.nih.gov/pubmed/23749113 http://dx.doi.org/10.3390/ijms140612273

Ejemplares similares

Inhibition of PIM2 in liver cancer decreases tumor cell proliferation in vitro and in vivo primarily through the modulation of cell cycle progression
por: Kronschnabl, Pia, et al.
Publicado: (2019)

Development of Biarylalkyl Carboxylic Acid Amides with Improved Anti‐schistosomal Activity
por: Peter Ventura, Alejandra M., et al.
Publicado: (2019)

Broad-spectrum antiviral activity of the eIF4A inhibitor silvestrol against corona- and picornaviruses
por: Müller, Christin, et al.
Publicado: (2018)

Hexamer phasing governs transcription initiation in the 3′-leader of Ebola virus
por: Bach, Simone, et al.
Publicado: (2020)

Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (−) and the eIF4A-inhibitor Silvestrol
por: Müller, Christin, et al.
Publicado: (2020)

Northern blot detection of endogenous small RNAs (∼14 nt) in bacterial total RNA extracts
por: Beckmann, Benedikt M., et al.
Publicado: (2010)

Targeting the DEAD-Box RNA Helicase eIF4A with Rocaglates—A Pan-Antiviral Strategy for Minimizing the Impact of Future RNA Virus Pandemics
por: Taroncher-Oldenburg, Gaspar, et al.
Publicado: (2021)

Feud or Friend? The Role of the miR-17-92 Cluster in Tumorigenesis
por: Xiang, Jie, et al.
Publicado: (2010)

miR-17–92 cluster: ups and downs in cancer and aging
por: Grillari, Johannes, et al.
Publicado: (2010)

miR-17 acts as a tumor suppressor by negatively regulating the miR-17-92 cluster
por: Sweat, Yan, et al.
Publicado: (2021)

Silvestrol Inhibits Chikungunya Virus Replication
por: Henss, Lisa, et al.
Publicado: (2018)

Insects in anthelminthics research: Lady beetle-derived harmonine affects survival, reproduction and stem cell proliferation of Schistosoma mansoni
por: Kellershohn, Josina, et al.
Publicado: (2019)

The rocaglate CR-31-B (−) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo
por: Müller, Christin, et al.
Publicado: (2021)

Role of the miR-17∼92 cluster family in cerebellar and medulloblastoma development
por: Zindy, Frederique, et al.
Publicado: (2014)

Insights into Regulation of the miR-17-92 Cluster of miRNAs in Cancer
por: Fuziwara, Cesar Seigi, et al.
Publicado: (2015)

Roles of miR-17-92 Cluster in Cardiovascular Development and Common Diseases
por: Gu, Huanyu, et al.
Publicado: (2017)

Biology of MiR-17-92 Cluster and Its Progress in Lung Cancer
por: Zhang, Xinju, et al.
Publicado: (2018)

miR-17-92 cluster in osteoarthritis: Regulatory roles and clinical utility
por: Pan, Xuefeng, et al.
Publicado: (2022)

Prognostic Value of the miR-17~92 Cluster in Chronic Lymphocytic Leukemia
por: Chocholska, Sylwia, et al.
Publicado: (2023)

Germline deletion of the miR-17-92 cluster causes growth and skeletal defects in humans
por: de Pontual, Loïc, et al.
Publicado: (2011)

Upregulation of the miR-17-92 cluster and its two paraloga in osteosarcoma – reasons and consequences
por: Arabi, Leila, et al.
Publicado: (2014)

Expression, regulation and mechanism of action of the miR-17-92 cluster in tumor cells (Review)
por: Fang, Li-Li, et al.
Publicado: (2017)

Inhibition of miR-17~92 Cluster Ameliorates High Glucose-Induced Podocyte Damage
por: Fan, Xiaobao, et al.
Publicado: (2020)

Evaluation of Serum miR-17-92 Cluster as Noninvasive Biomarkers for Bladder Cancer Diagnosis
por: Wang, Jingyao, et al.
Publicado: (2021)

TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis
por: Díez-Ricote, Laura, et al.
Publicado: (2022)

Natural antiviral compound silvestrol modulates human monocyte‐derived macrophages and dendritic cells
por: Blum, Leonard, et al.
Publicado: (2020)

The Antileukemia Activity of Natural Product HQ17(3) Is Possibly Associated with Downregulation of miR-17-92 Cluster
por: Liao, Ya-Chun, et al.
Publicado: (2014)

miR-17-92a-1 cluster host gene (MIR17HG) evaluation and response to neoadjuvant chemoradiotherapy in rectal cancer
por: Molinari, Chiara, et al.
Publicado: (2016)

SRSF3 shapes the structure of miR‐17‐92 cluster RNA and promotes selective processing of miR‐17 and miR‐20a
por: Ratnadiwakara, Madara, et al.
Publicado: (2023)

Inhibition of Zika Virus Replication by Silvestrol
por: Elgner, Fabian, et al.
Publicado: (2018)

The miR-17 ∼ 92 Cluster: A Key Player in the Control of Inflammation during Rheumatoid Arthritis
por: Philippe, Lucas, et al.
Publicado: (2013)

The miR-17-92 cluster/QKI2/β-catenin axis promotes osteosarcoma progression
por: Yang, Hongbo, et al.
Publicado: (2018)

Upregulation of miR-17-92 cluster is associated with progression and lymph node metastasis in oesophageal adenocarcinoma
por: Plum, Patrick Sven, et al.
Publicado: (2019)

MicroRNAs of the mir-17~92 cluster regulate multiple aspects of pancreatic tumor development and progression
por: Quattrochi, Brian, et al.
Publicado: (2017)

The MicroRNA Family Both in Normal Development and in Different Diseases: The miR-17-92 Cluster
por: Bai, Xiaodan, et al.
Publicado: (2019)

Investigation of the role of the miR17-92 cluster in BMP9-induced osteoblast lineage commitment
por: Zhang, Yunyuan, et al.
Publicado: (2021)

The diagnostic and prognostic value of the miR-17-92 cluster in hepatocellular carcinoma: A meta-analysis
por: Lu, Fang, et al.
Publicado: (2022)

EXM 92-17 03/09/92
por: Daems, G
Publicado: (1992)

Cas9-mediated excision of proximal DNaseI/H3K4me3 signatures confers robust silencing of microRNA and long non-coding RNA genes
por: Janga, Harshavardhan, et al.
Publicado: (2018)

MicroRNA miR-92a-1 biogenesis and mRNA targeting is modulated by a tertiary contact within the miR-17∼92 microRNA cluster
por: Chaulk, Steven G., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_1e3k49vq9egoerstn3uhauhkom