Enhanced Inhibition of Bladder Cancer Cell Growth by Simultaneous Knockdown of Antiapoptotic Bcl-xL and Survivin in Combination with Chemotherapy

The overexpression of antiapoptotic genes, such as Bcl-xL and survivin, contributes to the increased survival of tumor cells and to the development of treatment resistances. In the bladder cancer cell lines EJ28 and J82, the siRNA-mediated knockdown of survivin reduces cell proliferation and the inh...

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Detalles Bibliográficos
Autores principales: Kunze, Doreen, Erdmann, Kati, Froehner, Michael, Wirth, Manfred P., Fuessel, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709786/
https://www.ncbi.nlm.nih.gov/pubmed/23749114
http://dx.doi.org/10.3390/ijms140612297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709786/
https://www.ncbi.nlm.nih.gov/pubmed/23749114
http://dx.doi.org/10.3390/ijms140612297

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