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Tracking the Interplay between Bound Peptide and the Lid Domain of DnaK, Using Molecular Dynamics

Hsp70 chaperones consist of two functional domains: the 44 kDa Nucleotide Binding Domain (NBD), that binds and hydrolyses ATP, and the 26 kDa Substrate Binding Domain (SBD), which binds unfolded proteins and reactivates them, utilizing energy obtained from nucleotide hydrolysis. The structure of the...

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Detalles Bibliográficos
Autores principales: Azoulay, Itzhaq, Kucherenko, Nataly, Nachliel, Esther, Gutman, Menachem, Azem, Abdussalam, Tsfadia, Yossi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709807/
https://www.ncbi.nlm.nih.gov/pubmed/23774839
http://dx.doi.org/10.3390/ijms140612675