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Endothelial Cells Potentiate Interferon-γ Production in a Novel Tripartite Culture Model of Human Cerebral Malaria

We have established a novel in vitro co-culture system of human brain endothelial cells (HBEC), Plasmodium falciparum parasitised red blood cells (iRBC) and peripheral blood mononuclear cells (PBMC), in order to simulate the chief pathophysiological lesion in cerebral malaria (CM). This approach has...

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Detalles Bibliográficos
Autores principales:	Khaw, Loke Tim, Ball, Helen J., Golenser, Jacob, Combes, Valery, Grau, Georges E., Wheway, Julie, Mitchell, Andrew J., Hunt, Nicholas H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709908/ https://www.ncbi.nlm.nih.gov/pubmed/23874969 http://dx.doi.org/10.1371/journal.pone.0069521

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