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Crucial Optimization of Translational Components towards Efficient Incorporation of Unnatural Amino Acids into Proteins in Mammalian Cells

The ability to site-specifically incorporate unnatural amino acids (UAAs) into proteins is a powerful tool in protein engineering. While dozens of UAAs have been successfully introduced into proteins expressed by Escherichia coli cells, it has been much more challenging to create tRNA and tRNA-Synth...

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Detalles Bibliográficos
Autores principales:	Xiang, Liang, Moncivais, Kathryn, Jiang, Faqin, Willams, Blake, Alfonta, Lital, Zhang, Zhiwen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709914/ https://www.ncbi.nlm.nih.gov/pubmed/23874413 http://dx.doi.org/10.1371/journal.pone.0067333

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