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CpG Methylation Changes within the IL2RA Promoter in Type 1 Diabetes of Childhood Onset
None of the polymorphic variants of the IL2RA gene found associated with Type 1 Diabetes (T1D) was shown to have a functional effect. To test if the epigenetic variation could play a role at this locus, we studied the methylation of 6 CpGs located within the proximal promoter of IL2RA gene in 252 T1...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709990/ https://www.ncbi.nlm.nih.gov/pubmed/23874506 http://dx.doi.org/10.1371/journal.pone.0068093 |