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Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease

BACKGROUND: Vitamin D insufficiency has been implicated in autoimmunity. ChIP-seq experiments using immune cell lines have shown that vitamin D receptor (VDR) binding sites are enriched near regions of the genome associated with autoimmune diseases. We aimed to investigate VDR binding in primary CD4...

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Detalles Bibliográficos
Autores principales:	Handel, Adam E, Sandve, Geir K, Disanto, Giulio, Berlanga-Taylor, Antonio J, Gallone, Giuseppe, Hanwell, Heather, Drabløs, Finn, Giovannoni, Gavin, Ebers, George C, Ramagopalan, Sreeram V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710212/ https://www.ncbi.nlm.nih.gov/pubmed/23849224 http://dx.doi.org/10.1186/1741-7015-11-163

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