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Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2

BACKGROUND: Insulin is tightly associated with cancer progression; however, mechanistic insights into such observations are poorly understood. Recent studies show that metabolic transformation is critical to cancer cell proliferation. Here, we attempt to understand the role of insulin in promotion o...

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Detalles Bibliográficos
Autores principales: Iqbal, Mohd Askandar, Siddiqui, Farid Ahmad, Gupta, Vibhor, Chattopadhyay, Shilpi, Gopinath, Prakasam, Kumar, Bhupender, Manvati, Siddharth, Chaman, Noor, Bamezai, Rameshwar NK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710280/
https://www.ncbi.nlm.nih.gov/pubmed/23837608
http://dx.doi.org/10.1186/1476-4598-12-72