Why should we care about fly tumors?: The case of JAK-STAT and EGFR cooperation in oncogenesis

Drosophila is proving to be a valuable model for studying aggressive tumors induced by the combined activation of EGFR and JAK-STAT signaling. Here we summarize some of the most recent data showing that tissue damage and the modulation of common pathway regulators are at the heart tumor progression...

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Detalles Bibliográficos
Autores principales: Hombría, James Castelli-Gair, Serras, Florenci
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710316/
https://www.ncbi.nlm.nih.gov/pubmed/24058803
http://dx.doi.org/10.4161/jkst.23203
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author Hombría, James Castelli-Gair
Serras, Florenci
author_facet Hombría, James Castelli-Gair
Serras, Florenci
author_sort Hombría, James Castelli-Gair
collection PubMed
description Drosophila is proving to be a valuable model for studying aggressive tumors induced by the combined activation of EGFR and JAK-STAT signaling. Here we summarize some of the most recent data showing that tissue damage and the modulation of common pathway regulators are at the heart tumor progression and metastasis.
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spelling pubmed-37103162013-09-19 Why should we care about fly tumors?: The case of JAK-STAT and EGFR cooperation in oncogenesis Hombría, James Castelli-Gair Serras, Florenci JAKSTAT Commentary Drosophila is proving to be a valuable model for studying aggressive tumors induced by the combined activation of EGFR and JAK-STAT signaling. Here we summarize some of the most recent data showing that tissue damage and the modulation of common pathway regulators are at the heart tumor progression and metastasis. Landes Bioscience 2013-04-01 2013-04-01 /pmc/articles/PMC3710316/ /pubmed/24058803 http://dx.doi.org/10.4161/jkst.23203 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Commentary
Hombría, James Castelli-Gair
Serras, Florenci
Why should we care about fly tumors?: The case of JAK-STAT and EGFR cooperation in oncogenesis
title Why should we care about fly tumors?: The case of JAK-STAT and EGFR cooperation in oncogenesis
title_full Why should we care about fly tumors?: The case of JAK-STAT and EGFR cooperation in oncogenesis
title_fullStr Why should we care about fly tumors?: The case of JAK-STAT and EGFR cooperation in oncogenesis
title_full_unstemmed Why should we care about fly tumors?: The case of JAK-STAT and EGFR cooperation in oncogenesis
title_short Why should we care about fly tumors?: The case of JAK-STAT and EGFR cooperation in oncogenesis
title_sort why should we care about fly tumors?: the case of jak-stat and egfr cooperation in oncogenesis
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710316/
https://www.ncbi.nlm.nih.gov/pubmed/24058803
http://dx.doi.org/10.4161/jkst.23203
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AT serrasflorenci whyshouldwecareaboutflytumorsthecaseofjakstatandegfrcooperationinoncogenesis

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