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Why should we care about fly tumors?: The case of JAK-STAT and EGFR cooperation in oncogenesis
Drosophila is proving to be a valuable model for studying aggressive tumors induced by the combined activation of EGFR and JAK-STAT signaling. Here we summarize some of the most recent data showing that tissue damage and the modulation of common pathway regulators are at the heart tumor progression...
Autores principales: | Hombría, James Castelli-Gair, Serras, Florenci |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710316/ https://www.ncbi.nlm.nih.gov/pubmed/24058803 http://dx.doi.org/10.4161/jkst.23203 |
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