STAT3 and the Hyper-IgE syndrome: Clinical presentation, genetic origin, pathogenesis, novel findings and remaining uncertainties

During recent years a number of primary immunodeficiencies resulting from impaired function of JAK-STAT molecules have been described. One of these is the Hyper-IgE syndrome (HIES) characterized by elevated IgE levels, eczema, recurrent staphylococcal skin and pulmonary infections and pleiotropic so...

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Detalles Bibliográficos
Autor principal: Mogensen, Trine H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710320/
https://www.ncbi.nlm.nih.gov/pubmed/24058807
http://dx.doi.org/10.4161/jkst.23435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710320/
https://www.ncbi.nlm.nih.gov/pubmed/24058807
http://dx.doi.org/10.4161/jkst.23435

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