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Mechanisms of chronic JAK-STAT3-SOCS3 signaling in obesity

Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signaling pathways are critical for the maintenance of homeostatic and developmental processes; however, deregulation and chronic activation of JAK-STAT3 results in numerous diseases. Among others, obesity is currently bein...

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Detalles Bibliográficos
Autores principales: Wunderlich, Claudia M., Hövelmeyer, Nadine, Wunderlich, F. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710326/
https://www.ncbi.nlm.nih.gov/pubmed/24058813
http://dx.doi.org/10.4161/jkst.23878