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Developmental alterations in the biophysical properties of Ca(v)1.3 Ca(2+) channels in mouse inner hair cells

Prior to hearing onset, spontaneous action potentials activate voltage-gated Ca(v)1.3 Ca(2+) channels in mouse inner hair cells (IHCs), which triggers exocytosis of glutamate and excitation of afferent neurons. In mature IHCs, Ca(v)1.3 channels open in response to evoked receptor potentials, causing...

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Detalles Bibliográficos
Autores principales: Inagaki, Akira, Lee, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710344/
https://www.ncbi.nlm.nih.gov/pubmed/23510940
http://dx.doi.org/10.4161/chan.24104